Antibacterial Activity and Active Fraction of Zingiber officinale Roscoe, Zingiber montanum (J.Koenig) Link ex A., and Zingiber zerumbet (L.) Roscoe ex Sm. Against Propionibacterium acnes

Background: Propionibacterium acnes is a commensal bacteria that play role in developing acne vulgaris on the skin. Antibacterial activity assay last decades have shown resistant to several antibiotics. Potential zingiber genera such as Z. officinale, montanum, and zerumbet potential antibacterial. Objective: This study aims compare antibacterial of montanum against acnes, active fraction, components fraction plant. Materials Methods: test using agar diffusion method, extracts with high were partitioned water: n-hexane, n-hexane: methanol, ethyl acetate. The was tested for P. acnes. obtained identified its phytochemical content TLC GC-MS methods. Results: results officinale extract had larger inhibition zone. higher than extract. screening method main from volatile oil (?-curcumene, ?-zingiberene zingerone) oleoresin (6-shogaol). Conclusion: Extracts highest both acetate which known contain terpenoids compounds Key words: Antibacterial, Zingiber zerumbeth,